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Newly-Discovered Gene Variant , Could Help Prevent or Treat , Alzheimer's Disease.<br/>'Newsweek' reports that scientists have uncovered <br/>a genetic variant that has the potential to reduce <br/>the odds of developing Alzheimer's by as much as 70%.<br/>The discovery could reportedly lead to new methods to <br/>effectively treat or prevent the disease which impacts <br/>approximately 5.8 million people in the United States alone.<br/>Some genetic variants have been found to have an <br/>association with an increased likelihood of developing <br/>the disease, while other variants offer protection. .<br/>A team from Columbia University found that <br/>genes involved with the production of fibronectin <br/>play a crucial role in developing Alzheimer's.<br/>Healthy individuals usually only have fibronectin present <br/>in small amounts along their blood-brain barrier, while <br/>those with Alzheimer's have much higher quantities.<br/>It's a classic case of too much <br/>of a good thing. It made us think <br/>that excess fibronectin could be <br/>preventing the clearance of [abnormal <br/>protein clumps] from the brain, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The team believes that methods aimed at reducing <br/>fibronectin could play a crucial role in developing <br/>new treatments and preventative measures. .<br/>Anything that reduces excess <br/>fibronectin should provide some <br/>protection, and a drug that does <br/>this could be a significant step <br/>forward in the fight against <br/>this debilitating condition, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>Our findings suggest that...<br/>we may be able to develop new <br/>types of therapies that mimic <br/>the gene's protective effect <br/>to prevent or treat the disease, Caghan Kizil, co-leader of the study and professor of <br/>neurological sciences at Columbia University's Vagelos <br/>College of Physicians and Surgeons, via 'Newsweek'.<br/>The Columbia University team's <br/>findings were published in the <br/>journal 'Acta Neuropathologica.'
⏲ 1:31 👁 14.3M
Kathleen Hema
⏲ 11 minutes 25 seconds 👁 2.1K
wraith
⏲ 1 minute 30 seconds 👁 7.8K
SINCE losing 50kg and battling Lipedema, a young woman from Germany finally feels confident in her own skin. Sina-Laureen, 28, from Rostock, has struggled with her weight for years after being diagnosed with Lipedema, a disorder which causes an abnormal build-up of fat in the legs and arms, in 2017. At the beginning of 2020, Sina decided enough was enough. She told Truly: “I knew I had to change something, I couldn’t go on like this.”
⏲ 4:35 👁 3.4M
Breathtaking Recap
⏲ 24 seconds 👁 924.2K
The Fugitive
⏲ 25 minutes 59 seconds 👁 473.1K
A toddler born with a cyst the size of a pineapple under her arm is so heavy her spine has started to curve.<br/><br/>Jessi Campbell, two, was born with an estimated 1kg growth on her left arm, chest and fingers.<br/><br/>She was diagnosed with lymphatic malformation before birth – where lymph vessels form abnormally – and Kippel-Trelauney Syndrome at 11-months-old in July 2022. <br/><br/>The syndrome is a collection of symptoms - port wine stains, varicose veins and hypertrophy which is the extra growth of a limb. <br/><br/>Jessi has had three rounds of sclerotherapy – where a solution is injected into the veins to make the lymph collapse and shrink the cyst - and will continue to have more.<br/><br/>She took longer to walk – due to her balance – and is now struggling with a curved spine due to the weight of her arm. <br/><br/>The weight of her arm changes \
⏲ 0:46 👁 6.6M
SunflowerScreenings
⏲ 1 minute 👁 3.5M
Evil Days
⏲ 15 minutes 54 seconds 👁 1.1M
Killed while saving a stranger from a traffic collision, a 34-year-old neet is reincarnated into a world of magic as Rudeus Greyrat. With knowledge, experience, and regrets from his previous life retained, Rudeus vows to lead a fulfilling life and not repeat his past mistakes. Now gifted with a tremendous amount of magical power as well as the mind of a grown adult, Rudeus is seen as a genius in the making by his new parents. Soon, he finds himself studying under powerful warriors, such as his swordsman father and a mage named Roxy Migurdia—all in order to hone his apparent talents. But despite his innocent exterior, Rudeus is still a perverted otaku, who uses his wealth of knowledge to make moves on women whom he could never make in his previous life.
⏲ 23:40 👁 20K
This Prank
⏲ 2 minutes 26 seconds 👁 1.9K
Dr. Phil
⏲ 4 minutes 4 seconds 👁 6.2M
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